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WHAT'S NEW
FDA Issues Boxed Warning for Clopidogrel
The FDA has added a Boxed Warning to clopidogrel (Plavix®), the anti-blood clotting medication. The Boxed Warning is relevant to patients who do no effectively metabolize the drug and therefore may not receive its full benefits. For more information, click here.

FDA Alert on Clopidogrel and Proton Pump Inhibitors
The FDA is alerting the public to new safety information concerning an interaction between clopidogrel, an anti-clotting medication, and omeprazole, a proton pump inhibitor (PPI) used to reduce stomach acid. New data show that the effectiveness of clopidogrel is reduced when both agents are taken together. For more information and to view the full report, click here.

New Slides and Current Literature
Learn the latest results from the ARBITER 6-HALTS Trial.

2 Clinician's Challenge Activities Available
Expert Panel Members Christopher P. Cannon, MD, and Matthew J. Price, MD, offer thought-provoking clinical scenarios that affect your daily practice. Earn a total of 1.25 AMA PRA Category 1 Credits instantly.

New Interactive Case Study: 1 Patient, 3 ACS, 8 Antithrombotics in 11 Days!
Expert Panel Member Christopher P. Cannon, MD, and Michelle O’Donoghue, MD, manage a patient over the course of 11 days. As the patient experiences three acute coronary syndromes, the cardiologists must place five different stents and continually reassess the patient's antiplatelet regimen. Evaluate alternative therapy options for difficult cases. Earn 0.75 AMA PRA Category 1 Credit™ instantly!

Participate in Our Latest Audio Journal Club
Expert Panel Members David J. Schneider, MD, and Steven D. Wiviott, MD, discuss TRITON-TIMI 38. Earn 0.75 AMA PRA Category 1 Credits™ instantly!

A Journal Club for Primary Care—Intervention & Prevention: Keeping Current with ACS
Issue 6 now available! The Acute Coronary Syndrome Journal Club summarizes key scientific advances and clinical lessons from the literature and presents commentary and insight from recognized experts in the field who treat patients with ACS.

SLIDES OF THE MONTH

 
slide CHAMPION PCI: Design
Cangrelor versus Standard Therapy to Achieve Optimal Management of Platele...

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slide CHAMPION PCI: Composite Endpoint of Death from Any Cause, Myocardial Infarction, or Ischemia-Driven Revascularization
Cangrelor versus Standard Therapy to Achieve Optimal Management of P...

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slide CHAMPION PCI: Major Bleedinga
Cangrelor versus Standard Therapy to Achieve Optimal Management of Platele...

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slide CV Outcomes and Mortality Among Subjects Using Clopidogrel With PPI: Design
Rassen and colleagues assessed cardiovascular outcomes and mortality among subjects us...

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slide CV Outcomes and Mortality Among Subjects Using Clopidogrel With PPI
Rassen and colleagues assessed cardiovascular outcomes and mortality among...

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slide PCI PROVE-IT: Effect of Intensive Statin Therapy on MACE Among Subjects Undergoing PCI
Gibson and colleagues assessed the use of intensive vs standard statin therapy for red...

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slide ZEST-AMI: Design
  Lee and colleagues compared outcomes using three types of drug-eluting...

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slide ZEST-AMI: Rate of MACE at 12 Months
Lee and colleagues compared outcomes using three types of drug-eluting stent...

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slide Predictors of Early Stent Thrombosis in Subjects With ACS: Design
This study sought to determine the incidence and predictors of early stent...

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slide Independent Correlates of Early Stent Thrombosis
This study sought to determine the incidence and predictors of early stent...

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slide PLATO: Ticagrelor Vs Clopidogrel in Subjects With Planned Invasive Strategy for ACS: Primary Endpoint
The Study of PLATelet Inhibition and Patient Outcomes (PLATO) was a multic...

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slide PLATO: Ticagrelor Vs Clopidogrel in Subjects with Planned Invasive Strategy for ACS
The Study of PLATelet Inhibition and Patient Outcomes (PLATO) was a multic...

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slide ARBITER 6–HALTS: Effect of Niacin ER or Ezetimibe on CIMT
This prospective, randomized, parallel-group, open-label study with blinded endpoint evaluatio...

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slide Results from ARBITER 6–HALTS: Effect of Niacin ER or Ezetimibe on CIMT
This prospective, randomized, parallel-group, open-label study with blinded endpoint eva...

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slide ARBITER 6–HALTS: Methods and Final Results
Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6&mdas...

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slide ARBITER 6–HALTS: Final Results
Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6&mdas...

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Copyright 2008 Medical News Today
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